The primary aim of the Working Group for Functional Nucleic Acids – Aptamers is to develop new and innovative products that are based on aptamers. This involves both the generation, synthesis and functionalization of aptamers, as well as their integration in various applications. At the same time, the goal is to work closely with industry and research institutes.
Aptamers are mainly short single-strand DNA and RNA molecules that exhibit the special property – much like antibodies – of highly affine and highly specific binding to target molecules. The extremely wide range of uses for aptamers in analytical, diagnostic and therapeutic applications makes them highly universal binding molecules.
Special focus is given to the production of new aptamers using an automated in-vitro selection process and an efficient monitoring and management process, as well as the development of aptamer-based detection methods, such as strip tests or so-called aptasensors.