PD Dr. Harlad Seitz

leads the Biomarker Validation and Assay Development Group

Scientific focus and expertise

Harald Seitz - ORCID: 0000-0003-2939-8131
  • Hallier, D. C., Smales, G. J., Seitz, H., & Hahn, M. B. (2023). Bio-SAXS of single-stranded DNA-binding proteins: Radiation protection by the compatible solute ectoine. Physical Chemistry Chemical Physics : PCCP, 25(7), 5372–5382. https://doi.org/10.1039/D2CP05053F
  • Pellegrino, A., Fabig, S.-C., Kersebaum, D., Hüllemann, P., Baron, R., Roch, T., Babel, N., & Seitz, H. (2023). Differential Expression of microRNAs in Serum of Patients with Chronic Painful Polyneuropathy and Healthy Age-Matched Controls. Biomedicines, 11(3), 764. https://doi.org/10.3390/biomedicines11030764
  • Pellegrino, A., Danne, D., Weigel, C., & Seitz, H. (2023). An In Vitro Assay to Quantify Effects of Micro- and Nano-Plastics on Human Gene Transcription. Microplastics, 2(1), 122–131. https://doi.org/10.3390/microplastics2010009
  • Blazquez-Navarro, A., Bauer, C., Wittenbrink, N., Wolk, K., Sabat, R., Dang-Heine, C., Neumann, S., Roch, T., Wehler, P., Blazquez-Navarro, R., Olek, S., Thomusch, O., Seitz, H., Reinke, P., Hugo, C., Sawitzki, B., Babel, N., & Or-Guil, M. (2022). Early prediction of renal graft function: Analysis of a multi-center, multi-level data set. Current Research in Translational Medicine, 70(3), 103334. https://doi.org/10.1016/j.retram.2022.103334
  • Pellegrino, A., Mükusch, S., Seitz, V., Stein, C., Herberg, F. W., & Seitz, H. (2022). Transient Receptor Potential Vanilloid 1 Signaling Is Independent on Protein Kinase A Phosphorylation of Ankyrin-Rich Membrane Spanning Protein. Medical Sciences (Basel, Switzerland), 10(4). https://doi.org/10.3390/medsci10040063
  • Blazquez-Navarro, A., Bauer, C., Wittenbrink, N., Wolk, K., Sabat, R., Dang-Heine, C., Neumann, S., Roch, T., Wehler, P., Blazquez-Navarro, R., Olek, S., Thomusch, O., Seitz, H., Reinke, P., Hugo, C., Sawitzki, B., Babel, N., & Or-Guil, M. (2021). Early prediction of renal graft function: Analysis of a multi-centre, multi-level data set (Vol. 20). https://doi.org/10.1101/2021.01.04.20248473
  • Blazquez-Navarro, A., Dang-Heine, C., Wehler, P., Roch, T., Bauer, C., Neumann, S., Blazquez-Navarro, R., Kurchenko, A., Wolk, K., Sabat, R., Westhoff, T. H., Olek, S., Thomusch, O., Seitz, H., Reinke, P., Hugo, C., Sawitzki, B., Or-Guil, M., & Babel, N. (2021). Risk factors for Epstein-Barr virus reactivation after renal transplantation: Results of a large, multi-centre study. Transplant International : Official Journal of the European Society for Organ Transplantation, 34(9), 1680–1688. https://doi.org/10.1111/tri.13982
  • Morschheuser, L., Mükusch, S., Riedner, M., Seitz, H., & Rohn, S. (2016). High-performance thin-layer chromatography as a fast screening tool for phosphorylated peptides. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1008, 198–205. https://doi.org/10.1016/j.jchromb.2015.11.055
  • Schumacher, S., & Seitz, H. (2016). A novel immunoassay for quantitative drug abuse screening in serum. Journal of Immunological Methods, 436, 34–40. https://doi.org/10.1016/j.jim.2016.06.004
  • Schumacher, S., & Seitz, H. (2016). Quality control of antibodies for assay development. New Biotechnology, 33(5 Pt A), 544–550. https://doi.org/10.1016/j.nbt.2016.02.001
  • Hahn, M. B., Solomun, T., Wellhausen, R., Hermann, S., Seitz, H., Meyer, S., Kunte, H.-J., Zeman, J., Uhlig, F., Smiatek, J., & Sturm, H. (2015). Influence of the Compatible Solute Ectoine on the Local Water Structure: Implications for the Binding of the Protein G5P to DNA. The Journal of Physical Chemistry. B, 119(49), 15212–15220. https://doi.org/10.1021/acs.jpcb.5b09506
  • Schumacher, S., & Seitz, H. (2015). Multiplex approach for an immunological detection of drug abuse: a validation study. Toxichem. Krimtech82, 151-154.
  • Seitz, H., & Schumacher, S. (2015). Biomarker Validation. Wiley. https://doi.org/10.1002/9783527680658
  • Schumacher, S., Muekusch, S., & Seitz, H. (2015). Up-to-Date Applications of Microarrays and Their Way to Commercialization. Microarrays (Basel, Switzerland), 4(2), 196–213. https://doi.org/10.3390/microarrays4020196

  • ELISA
  • Lateral Flow Assay
  • Label-free assays: Biacore, bScreen, Nanotemper
  • Liquid handling and dispensing systems
  • Various microarrays (production, assay development and evaluation)
  • Various detection methods (e.g. optical, fluorescence, calorimetric)