Dr. Eva Ehrentreich-Förster

is acting director of the institute and department head of the research group Molecular and Cellular Bioanalytics

  • Kern, K., Havenith, H., Delaroque, N., Rautenberger, P., Lehmann, J., Fischer, M., Spiegel, H., Schillberg, S., Ehrentreich-Foerster, E., Aurich, S., Treudler, R., & Szardenings, M. (2019). The immunome of soy bean allergy: Comprehensive identification and characterization of epitopes. Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 49(2), 239–251. https://doi.org/10.1111/cea.13285
  • Agocs, E., Kozma, P., Nador, J., Hamori, A., Janosov, M., Kalas, B., Kurunczi, S., Fodor, B., Ehrentreich-Förster, E., Fried, M., Horvath, R., & Petrik, P. (2017). Grating coupled optical waveguide interferometry combined with in situ spectroscopic ellipsometry to monitor surface processes in aqueous solutions. Applied Surface Science, 421(1), 289–294. https://doi.org/10.1016/j.apsusc.2016.07.166
  • Memczak, H., Lauster, D., Kar, P., Di Lella, S., Volkmer, R., Knecht, V., Herrmann, A., Ehrentreich-Förster, E., Bier, F. F., & Stöcklein, W. F. M. (2016). Anti-Hemagglutinin Antibody Derived Lead Peptides for Inhibitors of Influenza Virus Binding. PloS One, 11(7), e0159074. 10.1371/journal.pone.0159074.
  • Kozma, P., Kehl, F., Ehrentreich-Förster, E., Stamm, C., & Bier, F. F. (2014). Integrated planar optical waveguide interferometer biosensors: A comparative review. Biosensors & Bioelectronics, 58, 287–307. https://doi.org/10.1016/j.bios.2014.02.049
  • Kozma, P., Lehmann, A., Wunderlich, K., Michel, D., Schumacher, S., Ehrentreich-Förster, E., & Bier, F. F. (2013). A novel handheld fluorescent microarray reader for point-of-care diagnostic. Biosensors & Bioelectronics, 47, 415–420. https://doi.org/10.1016/j.bios.2013.03.043
  • Schumacher, S., Lüdecke, C., Ehrentreich-Förster, E., & Bier, F. F. (2013). Platform technologies for molecular diagnostics near the patient's bedside. Advances in Biochemical Engineering/biotechnology, 133, 75–87. https://doi.org/10.1007/10_2012_165
  • Ettlinger, J., Schenk, J. A., Micheel, B., Ehrentreich-Förster, E., & Gajovic-Eichelmann, N. (2012). A Direct Competitive Homogeneous Immunoassay for Progesterone - the Redox Quenching Immunoassay. Electroanalysis, 24(7), 1567–1575. https://doi.org/10.1002/elan.201200107
  • Heise, C., Ehrentreich-Förster, E., & Bier, F. F. (2012). Dansyl, a fluorescent photoprotecting group for microarray applications. Journal of Chemical Technology & Biotechnology, 87(11), 1584–1592. https://doi.org/10.1002/jctb.3796
  • Schumacher, S., Nestler, J., Otto, T., Wegener, M., Ehrentreich-Förster, E., Michel, D., Wunderlich, K., Palzer, S., Sohn, K., Weber, A., Burgard, M., Grzesiak, A., Teichert, A., Brandenburg, A., Koger, B., Albers, J., Nebling, E., & Bier, F. F. (2012). Highly-integrated lab-on-chip system for point-of-care multiparameter analysis. Lab on a Chip, 12(3), 464–473. https://doi.org/10.1039/c1lc20693a
  • Schenk, J. A., Fettke, J., Lenz, C., Albers, K., Mallwitz, F., Gajovic-Eichelmann, N., Ehrentreich-Förster, E., Kusch, E., & Sellrie, F. (2012). Secretory leukocyte protease inhibitor (SLPI) might contaminate murine monoclonal antibodies after purification on protein G. Journal of Biotechnology, 158(1-2), 34–35. https://doi.org/10.1016/j.jbiotec.2011.12.025
  • Schumacher, S.; Sartorius, D.; Ehrentreich-Förster, E.; Bier, F. F. (2012) Miniaturization for Point-of-Care Analysis: Platform Technology for Almost Every Biomedical Assay. EJIFCC.
  • Griessner, M., Hartig, D., Christmann, A., Pohl, C., Schellhase, M., & Ehrentreich-Förster, E. (2011). Development and characterization of a disposable plastic microarray printhead. Biomedical Microdevices, 13(3), 533–538. https://doi.org/10.1007/s10544-011-9522-x
  • Bier, F. F., Ehrentreich-Förster, E., & Schumacher, S. (2010). Zeitvorteil-Plattformtechnologie für das Labor von morgen schon heute greifbar.
  • Grießner, M., Hartig, D., Christmann, A., Ehrentreich-Förster, E., Warsinke, A., & Bier, F. F. (2010). Surface regeneration of microfluidic microarray printheads through plasma techniques. Journal of Micromechanics and Microengineering, 20(3), 37002. https://doi.org/10.1088/0960-1317/20/3/037002
  • Ehrentreich-Förster, E., & Andresen, D. (2009). Marktpotenzial von Point-of-Care-Testing / Market potential of point-of-care testing. LaboratoriumsMedizin, 33(3), 153–157. https://doi.org/10.1515/JLM.2009.027
  • GGriessner, M., Bröker, P., Lehmann, A., Ehrentreich-Förster, E., & Bier, F. F. (2009). Detection of angiotensin II type 1 receptor ligands by a cell-based assay. Analytical and Bioanalytical Chemistry, 395(6), 1937–1940. https://doi.org/10.1007/s00216-009-3074-4
  • Nagel, T., Ehrentreich-Förster, E., & Bier, F. F. (2009). Label-free serodiagnosis on a grating coupler. Methods in Molecular Biology (Clifton, N.J.), 503, 189–200. https://doi.org/10.1007/978-1-60327-567-5_10
  • Bier, F. F., Nickisch-Rosenegk, M. von, Ehrentreich-Förster, E., Reiss, E., Henkel, J., Strehlow, R., & Andresen, D. (2008). Dna microarrays. Advances in Biochemical Engineering/biotechnology, 109, 433–453. https://doi.org/10.1007/10_2007_087
  • Ehrentreich-Förster, E., Orgel, D., Krause-Griep, A., Cech, B., Erdmann, V. A., Bier, F., Scheller, F. W., & Rimmele, M. (2008). Biosensor-based on-site explosives detection using aptamers as recognition elements. Analytical and Bioanalytical Chemistry, 391(5), 1793–1800. https://doi.org/10.1007/s00216-008-2150-5
  • Brandenburg, A., Curdt, F., Sulz, G., Schmitt, K., Ebling, F., Ehrentreich-Förster, E., & Bier, F. (2008). Biochip-readout for point of care diagnostics. https://doi.org/10.24406/publica-fhg-360938
  • Nagel, T., Ehrentreich-Förster, E., Singh, M., Schmitt, K., Brandenburg, A., Berka, A., & Bier, F. F. (2008). Direct detection of tuberculosis infection in blood serum using three optical label-free approaches. Sensors and Actuators B: Chemical, 129(2), 934–940. https://doi.org/10.1016/j.snb.2007.10.009
  • Antwerpen, M. H., Schellhase, M., Ehrentreich-Förster, E., Bier, F., Witte, W., & Nübel, U. (2007). Dna microarray for detection of antibiotic resistance determinants in Bacillus anthracis and closely related Bacillus cereus. Molecular and Cellular Probes, 21(2), 152–160. https://doi.org/10.1016/j.mcp.2006.10.002
  • Holländer, A., Kröpke, S., & Ehrentreich-Förster, E. (2007). Structured R2R Functionalisation of Polymer Film Surfaces by a Xenon Excimer Lamp. Plasma Processes and Polymers, 4(S1), S1052-S1056. https://doi.org/10.1002/ppap.200732404
  • Antwerpen, M., Schellhase, M., Ehrentreich-Forster, E., Bier, F., Witte, W., & Nubel, U. (2006). Evaluation of a DNA-microarray for rapid genotyping and detection of relevant genetic antibiotic resistance determinants in Bacillus anthracis and Bacillus cereus.
  • Andresen, H., Grötzinger, C., Zarse, K., Birringer, M., Hessenius, C., Kreuzer, O. J., Ehrentreich-Förster, E., & Bier, F. F. (2006). Peptide microarrays with site-specifically immobilized synthetic peptides for antibody diagnostics. Sensors and Actuators B: Chemical, 113(2), 655–663. https://doi.org/10.1016/j.snb.2005.07.033
  • Andresen, H., Grötzinger, C., Zarse, K., Kreuzer, O. J., Ehrentreich-Förster, E., & Bier, F. F. (2006). Functional peptide microarrays for specific and sensitive antibody diagnostics. Proteomics, 6(5), 1376–1384. https://doi.org/10.1002/pmic.200500343
  • Ruf, H. H., Knoll, T., Misiakos, K., Haupt, R. B., Denninger, M., Larsen, L. B., Petrou, P. S., Kakabakos, S. E., Ehrentreich-Förster, E., & Bier, F. F. (2006). Biochip-compatible packaging and micro-fluidics for a silicon opto-electronic biosensor. Microelectronic Engineering, 83(4-9), 1677–1680. https://doi.org/10.1016/j.mee.2006.01.182
  • Ehrentreich-Förster, E., Bier, F. F., & Kreuzer, O. J. (2006). Development of peptide microarrays for epitope mapping of antibodies against the human TSH receptor. Journal of Immunological Methods, 315(1-2), 11–18. https://doi.org/10.1016/j.jim.2006.06.012
  • Nickisch-Rosenegk, M. von, Ehrentreich-Forster, E., Strehlow, R., Christmann, A., & Bier, F. F. (2005). Chemically synthesized zinc finger molecules as nano-addressable probes for double-stranded DNAs. Journal of Nanobiotechnology, 3, 5. https://doi.org/10.1186/1477-3155-3-5
  • Misiakos, K., Petrou, P. S., Kakabakos, S. E., Ruf, H. H., Ehrentreich-Förster, E., & Bier, F. F. (2005). A bioanalytical microsystem for protein and DNA sensing based on a monolithic silicon optoelectronic transducer. Journal of Physics: Conference Series, 10, 273–276. https://doi.org/10.1088/1742-6596/10/1/067
  • Henkel, J., Ehrentreich-Förster, E., & Bier, F. F. (2005). Chip based immunoassays for diagnostic of autoimmun antibodies as an alternative to cell based bioassays. GBM Annual Fall Meeting Berlin/Potsdam 2005, 2005(Fall). https://doi.org/10.1240/sav_gbm_2005_h_001393
  • Andresen, H., Zarse, K., Grötzinger, C., Kreuzer, O. J., Hollidt, J. M., Ehrentreich-Förster, E., & Bier, F. F. (2005). Miniaturized Multiplexed Immunoassays for Antibody Detection and Characterization with Peptide Microarrays. GBM Annual Fall Meeting Berlin/Potsdam 2005, 2005(Fall). https://doi.org/10.1240/sav_gbm_2005_h_001335
  • Münch, Y., Ehrentreich-Förster, E., Henkel, J., & Bier, F. F. (2005). Development of a protein chip for the detection of anti-gliadin autoimmune antibodies. GBM Annual Fall Meeting Berlin/Potsdam 2005, 2005(Fall). https://doi.org/10.1240/sav_gbm_2005_h_001417
  • Bier, F. F., Ehrentreich-Förster, E., & Schmidt, P. M. (2004). Real-time analysis on microarrays. Analytical and Bioanalytical Chemistry, 378(1), 52–53. https://doi.org/10.1007/s00216-003-2375-2
  • Schwonbeck, S., Krause-Griep, A., Gajovic-Eichelmann, N., Ehrentreich-Förster, E., Meinl, W., Glatt, H., & Bier, F. F. (2004). Cohort analysis of a single nucleotide polymorphism on DNA chips. Biosensors and Bioelectronics, 20(5), 956–966. https://doi.org/10.1016/j.bios.2004.06.012
  • Ehrentreich-Forster, E., Heise, C., Gajovic-Eichelmann, N., Schwonbeck, S., Schmidt, P. M., & Bier, F. F. (2004). Biochips-Einsatzmoglichkeiten im LaboralltagLABORPRAXIS-WURZBURG-28(1/2), 16-21.
  • Gajovic-Eichelmann, N., Ehrentreich-Förster, E., & Bier, F. F. (2003). Directed immobilization of nucleic acids at ultramicroelectrodes using a novel electro-deposited polymer. Biosensors and Bioelectronics, 19(5), 417–422. https://doi.org/10.1016/S0956-5663(03)00224-0
  • Ehrentreich-Förster, E., Scheller, F. W., & Bier, F. F. (2003). Detection of progesterone in whole blood samples. Biosensors and Bioelectronics, 18(4), 375–380. https://doi.org/10.1016/S0956-5663(02)00145-8
  • Ehrentreich-Förster, E., Rimmele, M., Orgel, D., & Bier, F. F. (2003). On-site measurement of explosives and environmental hazards using a fibre optic biosensor.
  • Ehrentreich‐Förster, E., Schwonbeck, S., Schmidt, P. M., & Bier, F. F. (2003). Kinetische Analyse im Mikroarrayformat. Nachrichten aus der Chemie51(10), 1106-1108.
  • Ehrentreich-Förster, E., & Bier, F. F. (1999). Detektion von Progesteron in Vollblut mittels integriert optischem Gitterkoppler.

  • Dispensing of biological fluids / samples in pL to µL volume
  • Contact and non-contact based methods
  • Dispensing on different surfaces
  • Immobilization of (bio)molecules
  • Quality control of the produced microarrays
  • Surface characterization
  • Determination of loading / immobilization density
  • Modification and coating of surfaces