Equipment

Microscopy

  • Confocal laser scanning microscope (Zeiss LSM510)
  • Fluorescence microscopes, confocal laser scanning microscope with fluorescence correlation spectroscopy and fluorescence lifetime (FCS; FLIM; from 350 nm)
  • Fully automated fluorescence microscopy with climate-controlled object stages for long-term observation of living cells (Olympus Cell^R)
  • Atomic force microscopes (AFM, SNOM), partly air-conditioned
  • Scanning Electron Microscopy
  • Confocal scanning laser microscope with 3D image processing
  • Transmitted and reflected light microscopy with bright field, phase contrast, fluorescence, polarisation and total reflection (TIRFM),
  • highest resolution optical microscopy (SIM)
  • Cryomicroscope with digital image processing
  • TIRF microscopy (Olympus)
  • Computer-controlled and temperature-controlled object stages and cell culture chambers
  • Laser Tweezer / optical tweezers with laser microdissection (Palm / Zeiss)
  • Optical tweezers with combined UV laser for laser cutting
  • 32-channel radio frequency generators for dielectrophoretic particle manipulation

 

Processing

  • Electropolymerization plant
  • Nanolitre microdispenser
  • Microcontact Printer (GeSiM)
  • Hybridization stations for semi-automatic microarray processing
  • Non-contact liquid handling systems like I2-400
  • Variable Microfluidic Setup - Computer-controlled pump systems
  • Micromanipulation, microinjection, microdissection (Eppendorf)
  • 32-channel radio frequency generators for dielectrophoretic particle manipulation
  • Cell Processing
    • PCR workstation with HEPA filter
    • Protein & DNA purification:
      • KingFisher Duo Magnetic Partical Processor for SELEX process with plate function
      • KingFisher BioSprint 15 for SELEX process
  • Printing process 3D printing
    • Selective Laser Sintering (SLS)
    • Fused metal layer process (FDM)
    • Surface Exposure Level (SLA)
    • multijet technology
    • Selective laser melting (SLM)

 

Molecular biological analytics

  • Label-free biosensors (Biacore Flexchip, Biacore XT100)
  • MTP readers
    • Microtiter plate fluorometer
    • Microtiter plate spectrophotometer
    • Microscale thermophoresis (Nanotemper (Monolith NT.115))
  • Microarray Facilities
    • Biochip arrayer (Genpix, non-contact, Scienion S5 & S7, TopSpotter, i2 from M2)
    • bScreen - (Single Colour Reflectometry)
  • Bio-Plex® 3D Suspension Array System
  • multiplex assays
  • Biacore (X, TM T200)
  • Flow cytrometry (Becton D.)

 

Instrumental analytics

  • Ellipsometry, contact angle measurements
  • Gas chromatograph with FID detector (Agilent 7890B)
  • HPLC
  • Elemental analyser (EuroEA CNS)
  • Spectrophotometer UV/VIS
  • Fluorometer
  • Spectroscopy
  • MS analysis of peptides, proteins (identification, characterisation and investigation of modifications such as glycosylation, phosphorylation, palmitylation), protein-protein and protein-ligand interactions

 

Sensors

  • label-free MIP thermistor
  • Label-free biosensors
  • Quartz Crystal Microbalance (QCM)
  • Fibre-based and autonomous biosensors

 

Electronic measuring instruments

  • Oscilloscopes and spectrum analyzers up to 30 GHz or 20 ps
  • Vector network analyzers from 10 Hz to 110 GHz